Photo of Savannah Guthrie, Nancy Guthrie
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The Pima County Sheriff’s Office in Arizona issued a missing person’s alert for Nancy Guthrie, the 84-year-old mother of TODAY show host Savannah Guthrie.

Savannah skipped Monday’s TODAY show as the search continues for her mother. Volunteers from the Search and Rescue Association are assisting deputies.

Nancy was last seen at her home in Catalina Foothills, near Tucson, on Saturday, January 31. Homicide detectives are investigating.

Deputies don’t know what she was wearing when she went missing around 9:30 p.m. Saturday.

Sheriff Chris Nanos said investigators found “disturbing signs” at her home and she did not leave home on her own. Nanos said she is not in good physical health.

“This is very concerning to us. We don’t typically get the sheriff out at a scene like this. But it’s very concerning what we’re learning from the house,” Nanos told reporters. “And so we’ll just continue. The detective’s homicide team is out right now looking at the scene as well.”

“We’ve pretty much thrown everything at this as we can,” he added. In a follow-up presser on Monday morning, Nanos said, “we do in fact have a crime… It is a crime scene, we know that.”

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The sheriff said Nancy needs her daily medication, and he urged anyone who sees her to “take a quick picture.”

The family said Nancy did not show signs of dementia.

Friends shared their support for Savannah on X (Twitter).

ABC News journalist Deborah Roberts wrote: “My heart is hurting for Savannah Guthrie and her family as they search for her beloved mom. Praying and praying for her safe return!”