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Anne Heche (right) said her three-year lesbian romance with Ellen DeGeneres (left) ruined her movie career.

Heche met DeGeneres at a Vanity Fair party in 1997 and the pair soon began dating, but she admits her highly-publicized relationship with the comedienne deeply affected her career.

"My movie premiere for Volcano, I had told them (producers) that I was taking Ellen as my date and I was told if I took Ellen I would lose my Fox contract," she tells People magazine.

"At that moment, she took my hand and said, 'Do what they say' and I said, 'No thanks'. I took Ellen to the premiere and I was ushered out before the movie even ended and was told I was not allowed to go to my own after party for fear that they would get pictures of me with a woman.

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"She was warning me, 'This is going to happen'. I was in a relationship with Ellen DeGeneres for three-and-a-half years and the stigma attached to that relationship was so bad that I was fired from my multi-million dollar picture deal and I did not work in a studio picture for 10 years."

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DeGeneres and Heche split in August 2000 and Heche gave up the lesbian lifestyle.

Heche, 51, married Coleman Laffoon in September, 2001. She then moved on to a romance with actor James Tupper.

DeGeneres, 62, tied the knot with actress Portia De Rossi in 2008.