Comedian Bernie Mac has died according to his publicist. He was 50.

Mac's publicist Danica Smith said Mac died early Saturday morning from complications related to pneumonia. This same publicist denied Mac's pneumonia was related to Mac's chronic disease, sarcoidosis, which Smith claimed was in remission since 2005.

But what else could have caused Mac's pneumonia considering his past medical history?

As I explained in my earlier post (in layman's terms), sarcoidosis is an immune disorder that turns the body's cells against itself. It occurs mainly in the lungs and lymph nodes (such as in your armpits, chest, neck and groin) but it can also occur anywhere in the body such as your skin, liver and other body organs.

When sarcoidosis involves the skin, it causes tiny red bumps (granulomas) to develop. Inside the lungs, the bumps cause respiratory problems by clumping together, causing scarring and making it extremely difficult to breathe. Some patients with advanced sarcoidosis go on a ventilator.

Doctors don't know what causes sarcoidosis - other than it is an extreme autoimmune response to something external in the environment (such as poison, infection or other diseases) which leads the body's cells to replicate out of control.

In 60 to 70 percent of cases, symptoms will be vague or non-existent and most people won't know they have the disease. But if the disease involves the lungs, such as in Mac's case, the condition is more severe. Black people tend to develop the more severe form of sarcoidosis. There is no known cure.

Symptoms of lung involvement include:

    * Shortness of breath (dyspnea)
    * Breathing difficulty
    * Persistent productive cough
    * Chest pain
    * Chest tightness
    * fatigue (feeling tired all the time)
    * night sweats
    * fever
  • http://www.hiphossip.com Kemi at HipHossip Canada

    Great Medical Reporting coming from a nurse--Sandra. That is one very complicated disease and we need even more awareness. The other pneumonia complications can arise from the Acquired Immune Deficiency virus. AIDS--Hope he didn't die of that and we're not being told! I wasn't a Bernie Mac fan as I'm not into comedy. I've seen his show once and it was OK. R.I.P.....

  • Sharonda

    My sister just called and told me about this.Rest In Paradise.

  • MsShayinGA

    Good Morning America broke the news this morning around 9 and I was so sad to hear this, but I wasnt too shocked being that Stella Foster, journalist with the Chicago Sun-Times had mentioned all this week that a family member had told her his condition was critical. I guess his publicist was just doing what she was told to do :(

    CNN spoke with Steve Harvey this morning and he was really shook up because he had just learned of Bernie's death from Al Sharpton when they were sitting down eating breakfast in Chicago.

    RIP to the Mac Family.

  • donnia

    R.I.P Mac - My prayers are with his family during this very difficult time. I hope they can take solist (spelling?) in knowing he made his mark in this world. I will forever be a fan. - Love Ya Mac

  • bklynchick

    REST IN PEACE BERNIE MAC

    He was such a funny mN ns will be missed dearly.

  • NYCUTIE

    RIP!! I truly love this man! I am hurting!

  • http://www.myspace.com/fla_gyrl_rhia rhiannon

    Dang the king is gone!! There will never be another like him!! Thanks Sandra. Why hasn't BET reported this??!!

  • ReadTheBlog

    I'm glad I got an opportunity to see him perform in his career - as a fan, he will be missed . God be with his family...

  • MsShayinGA

    BET has it on the website, but you know they don't have a news center to break the story, nor does TVOne. They'll probably do a scroll @ the bottom of the screen later on today.

  • starr

    I was really sad to hear it this morning. A true king of comedy. There will never be another Bernie Mac.

  • dat803chic

    Right now i'm speechless.R.I.P. Bernie Mac!He was a great comedian and actor.He will be truly missed.My prayers are with his family and friends.

  • http://www.myspace.com/mrs_khan18 Quinetta1

    I am deeply sadden about his death but he was and still is a talented man and great comedian. I would just like to send my condolence once again to his family and friends. We'll never know what holds for us tomorrow, thats why we live for it and never look back on yesterday because there's no guarantee. I also would like to say I genuinely love everyone, even if we've never met I still do.

  • candi21

    R.I.P Bernie !! He was one of our greatest and funniest entertainers....

  • Lucy

    This is one time I can say someone I didn't know personally who died will affect me. Such a lost. R.I.P. Bernie. You brought me laughter and now tears.

    You will me missed.

  • Anna

    My morning went so well. I witnessed the graduation of 1300 ppl along with my daughter from college today. I even got an autograph form the guest speaker James Pinkens(the black older guy from Greys Anatomy) On the way home for a celebration of the graduation my son go a text that Bernie Mac passed away. I am so saddend and not in the mood to celebrrate. I extend my condolences to the Bernie Mac family and my prayers are with you.

    Sandra I read your post and you did answer my question about sarcadocis, is it/does it have any relation to sicle cell? These are diseases for only black ppl and the only disease in my household it "The Lazy Syndrome". On a real note I very much want the 411.

  • MsShayinGA

    Just had to add this classic Def Jam set of him. RIP.

    http://www.youtube.com/watch?v=RviYo3WsqjU

  • http://www.myspace.com/thegameoncw Bird

    Bye Bernie. You will be missed my brotha.

  • http://www.smokiesays.blogspot.com/ Smokie

    :-(

    R.I.P. Bernie... :-(

  • http://www.sandrarose.com Sandra Rose

    @ Anna:
    the two diseases are not related. Sarcoidosis is an immune disorder with an unknown environmental cause. While Sickle Cell is an inherited genetic blood disorder. Anyone can acquire sarcoidosis. But it is more prevalent among Africans probably because of the limited access to proper health care.

  • hellava10

    DAMN!!!!! So sad. God bless and keep his family. 50 is a really young! Keep yourself right amd love hard. He was funny as hell but it was vey obvious he had a huge heart.
    "stir it like MF coffee!!!!!!"

  • ELove

    Such a Terrible LOSS!!!
    He's a Homie and he's going to be Missed-So-Much
    WE ALL LOVE YOU B-Mac !!!!!

  • http://pleasurekisses.com Mika79

    I didn't realize how trully serious pneumonia is until my two year old had it and was on breathing treatments and almost had to have surgery. This is very sad to hear. Rest in Peace Bernie!

  • lailasimone

    R.I.P Bernie!!!! Its a sad day....

  • http://myspace.com/sfh50millionpounds mj

    I cried several times. It's really sad. Bernie Mac just cracked me up everytime he opened his mouth. He seemded so soft to be such a big man. He seemd to have a heart of gold and the comedy of gold. Our King of Comedy is now making folks laugh in Heaven and I'm a bit jealous they have him instead of us.. But we know God is waiting back stage to welcome him into Heavens Palace. And you can't beat that! R.I.P and may God bless his wife and family..

  • Anna

    Sandra Rose Says:

    @ Anna:
    the two diseases are not related. Sarcoidosis is an immune disorder with an unknown environmental cause. While Sickle Cell is an inherited genetic blood disorder. Anyone can acquire sarcoidosis. But it is more prevalent among Africans probably because of the limited access to proper health care.
    ~~~~~~~~~~~~~~~~~~
    Thanks Sandra.

  • Anna

    mj Says:

    I cried several times. It’s really sad. Bernie Mac just cracked me up everytime he opened his mouth. He seemded so soft to be such a big man. He seemd to have a heart of gold and the comedy of gold. Our King of Comedy is now making folks laugh in Heaven and I’m a bit jealous they have him instead of us.. But we know God is waiting back stage to welcome him into Heavens Palace. And you can’t beat that! R.I.P and may God bless his wife and family..
    ~~~~~~~~~~~~~~~~~~~
    My kids said "The King of Comedy died". I can bet you that he is laughing in heaven as he did on earth. His presence will be missed. I know GOD does what he does and we are not to challenge it but accept it. 50 is young though. I guess we should all do our own inventory and make ammends and pick up a bible or go to church tomorrow. Have A Great Journey In Heaven Bernie. I will not say R I P because I know you will not die, but live on and keep entertainig us. My prayers do once again go to the family and in my home via reruns Bernie Mac will live on.

  • VAALLDAY

    RIP Bernie Mac. Comedy has truly lost a legend. My prayers go out to the family.

  • missmiami

    Bernie Mac is the equivalent to Red Foxx to me. He will be missed. I can't believe he is gone and yet so very young. Life is truly short. I will listen to the Steve Harvey show on Monday cuz I know he will be devistated. I wonder what happened to the Original Kings of Comedy? I always hoped they would do a second tour. Truly a milestone and Bernie was always my favorite.

  • Kymystry

    I will remember where I was when I heard the news just like I remember where I was When Marvin Gaye was killed and 911.

    You WILL be miss Jank-a-leg ...

    One of the TRUE KANGS of COMEDY!!!

  • ms.peaches

    Wow, it was real sad to hear that I was actually watching TV One & they should a picture of him saying rest in peace I couldn't believe it!! he was truly a king & will be missed. I can only imagine what his family is going through, as well as his fellow kings of comedy!! I miss u Mac!!! Chi Town stand up!!!!

  • http://www.myspace.com/bettathaniwasb4 2bme

    I just watched an old Def Jam Comedy when we were first introduced to who Bernie was..he will really be missed...gone too soon

  • Tiffochris11

    Rip MAC!! He's in a better place,where i hope to be oneday! My Prayers go out to his family!

  • Anna

    Mr. Hayes also passed away. 65 years young. Another black man who has been in our homes durning our upbringing and adulthood. R I P Mr Hayes.

  • http://myspace.com/sfh50millionpounds mj

    Bernie Mac yesterday and Isasac Hayes today. Who is next! Trouble always comes in three's

  • Anna

    mj Says:

    Bernie Mac yesterday and Isasac Hayes today. Who is next! Trouble always comes in three’s.
    ~~~~~~~~~~~~~~~~
    I know and who is going to equal the 3rd. I will just hug and love the 2 black men in my home. Ny son and my husband. As a black person I do know that death does happen in 3's. Morgan Freeman is a blessed/lucky man. I know we are taugh that heaven is a beautiful place, Are we really ready to meet our destiny/maker. I don't want to leave my kids or family yet. I know it is GOD's will but I am not ready. I know my life is not mine and my kids are borrowed to me from GOD. I pray each night that all get the breath for another day to do better. I am not ready to leave my family.

  • Anna

    sorry for the typos.

  • http://xscape2xscape.com crystal

    R.I.P Bernie Mac and Isaak Hays. Gone but not forgotten R.I.P Curtis Mayfield.

  • http://www.myspace.com/shaylacheri MsShayinGA

    I just read another story on Bernie Mac. His daughter Je'Niece said that he had been in the hospital since mid-July..so were talking right after his appearance at Barack Obama's fundraiser. She said her and her mother hoped he would be able to go home, but after awhile they knew it was a possibility he could die and she said she knew it would be soon following last week. So sad.

    I was watching the Bud Billiken (sorry if its misspelled) on TVOne and Steve Harvey was hosting it with another lady from Chicago and both him and Al Sharpton said it still hasnt hit them yet.

  • starr

    What a weekend......

  • http://www.stylishmoms.net Nina

    RIP Bernie - you touched many lives and will be greatly missed!!!

    RIP to Isaac Hayes too!!!

  • http://pleasurekisses.com Mika79

    Issac and Bernie are both in the movie Soul Man that's about to come out...scary!

  • PAHairston

    The GREAT BERNIE MAC has gone to a better place, may he rest in piece. No one knows the date nor hour when God will call us home. We need to have our house in order.

    WE LOVE YOU BERNIE MAC and will miss your humor forever! Young men out there, take a lesson from Bernie and be good fathers to your children. May God bless us all.

  • PAHairston

    I meant: May he rest in peace. Peace.

  • aqtpie

    RIP Bernie Mac you will be greatly missed.

  • DMNB

    I was a really big fan of Bernie Mac, shock to hear that he had passed away.

  • Kymystry

    I just listened to the Steve Harvey Morning Show. His whole show was a tribute to B.Mac & Issac Hayes ... I feel like this was a personal loss and they will be missed.

    His tribute to B.Mac was SOOOO touching and heartfelt ..
    he had the Rest of the "Kings of Comedy" on the phone and All those men were hurting .. the main thing they stressed was .. they thought they had More time to go see him in the hosp .. and tell Bernie that they loved them .. and he slipped away before they got a chance to do so ...

    sigh ...

    You WILL be missed B.Mac.

  • candycane

    Awwwwwwwwwww Uncle Bernie RIP