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Jermaine Dupri rushed to defend his friend, Usher Raymond, when the R&B crooner teased his new single - and everyone thought he was singing about herpes.

According to TMZ, the diminutive music producer and part-time DJ, cleared the air when speculation ran rampant that Usher's new single "Confessions Pt. 3" contained a reference to his "sickness."

"Don't let that 'sickness' lyric fool you," JD tweeted on Wednesday. "The song is about a girl cheatin' on him and gettin' pregnant by another man. She is then being stuck with the decision to keep or abort it. Now that he knows, Should he stay or Leave???"

Usher teased the new single during his live set at the Cricket Lounge this week.

    "Remember that time I was sitting up sick, couldn't sleep on the middle of the night? / And you said bae let me take you to the ER / I said 'Nah, Imma be alright / Well, the next day I found out from f*cking around that the sickness I had was life / And I was fixed with the decision to keep it / Knowing I had to get rid of it, rid of it, live with it / You don't know, he don't know, I had to deal with it."

The song concludes with: "That's the test to see if you're strong."

Then, addressing the audience directly, Usher says, "You realize what I just told you? You don't realize it, huh? Well, you can play it back."