Rochester Mayor Lovely Warren denied any wrongdoing after her husband was arrested on drug trafficking charges Wednesday.
Timothy Granison, 43, was arrested during a raid of the couple's Rochester home as part of a months long drug trafficking sting.
Troopers sealed off the block around the mayor's home as police carried boxes and bags of evidence out of the home.
Seven others were also arrested and agents seized 2 kg of cocaine worth $60,000, three firearm, a rifle and $100,000 in cash.
Granison pleaded not guilty on Wednesday and was released without bail pending his next court hearing, the Dailymail.com reports.
Granison is no stranger to law enforcement. In 1997, when he was 17, he was arrested for his role in a jewelry store robbery. He was placed on probation for five years.
New York State Police Major Barry Chase said he hoped to interview the mayor as part of the investigation. However, the mayor's office is not responding to their calls.
In a press conference on Thursday, a somber Mayor Warren insisted she has "done nothing wrong" and she lashed out at police for the "highly suspicious" timing of her husband's arrest.
The mayor insisted she and Granison have been separated "for many years," but they are roommates who still live in the home that was raided.
The former couple share a 10-year-old daughter, Taylor, who was at home alone when state police took the front door off its hinges during the raid.
Warren, a Democrat, was indicted for campaign fraud last October. She is currently in the middle of a reelection campaign for a third term as mayor.